Statements (47)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Cell
|
| gptkbp:abbreviation |
gptkb:CHO_cell
|
| gptkbp:biosafetyLevel |
gptkb:BSL-1
|
| gptkbp:culture |
suspension
adherent |
| gptkbp:derivedFrom |
gptkb:Chinese_hamster_(Cricetulus_griseus)
|
| gptkbp:doublingTime |
12-14 hours
|
| gptkbp:firstIsolatedFrom |
1957
|
| gptkbp:genomeSize |
2.6 Gb
|
| gptkbp:growthMedium |
gptkb:DMEM/F12
gptkb:Ham's_F-12 |
| https://www.w3.org/2000/01/rdf-schema#label |
Chinese Hamster Ovary cell
|
| gptkbp:locatedOnChromosome |
22
|
| gptkbp:notableFeature |
easy genetic manipulation
glycosylation similar to humans high protein production capability |
| gptkbp:notableGroup |
gptkb:CHO-DG44
gptkb:CHO-K1 gptkb:CHO-Pro5 gptkb:CHO-S |
| gptkbp:notableProduct |
monoclonal antibodies
therapeutic proteins recombinant enzymes |
| gptkbp:originatedIn |
gptkb:Stanford_University
|
| gptkbp:repository |
gptkb:ATCC_CCL-61
gptkb:ECACC_85050302 |
| gptkbp:transfectionMethod |
electroporation
calcium phosphate precipitation lipofection |
| gptkbp:usedBy |
academic research
biotechnology industry pharmaceutical industry |
| gptkbp:usedFor |
protein engineering
cell biology research metabolic engineering vaccine production gene expression studies toxicology research toxicology screening biopharmaceutical production pharmacology research bioprocess optimization gene amplification studies glycosylation studies recombinant protein expression |
| gptkbp:bfsParent |
gptkb:CHO
|
| gptkbp:bfsLayer |
6
|