Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Cell
|
| gptkbp:advantage |
rapid growth
genetic instability high protein yield human-like post-translational modifications variable glycosylation patterns |
| gptkbp:biosafetyLevel |
gptkb:BSL-1
|
| gptkbp:commonSubtypes |
gptkb:CHO-K1
gptkb:CHO-S DG44 DXB11 |
| gptkbp:cultivatedIn |
adherent culture
suspension culture |
| gptkbp:firstIsolatedFrom |
1957
Theodore T. Puck |
| gptkbp:fullName |
Chinese hamster ovary cell
|
| gptkbp:geneticallyModified |
yes
|
| https://www.w3.org/2000/01/rdf-schema#label |
CHO cell
|
| gptkbp:organism |
gptkb:Cricetulus_griseus
|
| gptkbp:origin |
gptkb:Chinese_hamster_(Cricetulus_griseus)
|
| gptkbp:repository |
gptkb:ATCC_CCL-61
gptkb:ECACC_85050302 DSMZ ACC-110 |
| gptkbp:transfectionMethod |
electroporation
calcium phosphate precipitation lipofection |
| gptkbp:usedBy |
academic researchers
pharmaceutical companies biotech industry |
| gptkbp:usedFor |
cell biology research
metabolic engineering vaccine production gene expression studies toxicology testing drug screening biopharmaceutical manufacturing recombinant protein production monoclonal antibody production gene amplification studies glycosylation studies production of biosimilars production of therapeutic proteins protein glycosylation analysis toxicology assays |
| gptkbp:usedIn |
gptkb:biotechnology
biological research pharmaceutical production |
| gptkbp:bfsParent |
gptkb:Chinese_Hamster_Ovary_cell
|
| gptkbp:bfsLayer |
7
|