|
gptkbp:instanceOf
|
gptkb:drug
antihistamine
|
|
gptkbp:approvedBy
|
1987
|
|
gptkbp:ATCCode
|
gptkb:R06AE07
|
|
gptkbp:availableOn
|
gptkb:tablet
chewable tablet
oral solution
|
|
gptkbp:bioavailability
|
70%
|
|
gptkbp:brand
|
gptkb:Zyrtec
gptkb:Alleroff
gptkb:Reactine
|
|
gptkbp:CASNumber
|
83881-52-1
|
|
gptkbp:contraindication
|
severe renal impairment
hypersensitivity to cetirizine
|
|
gptkbp:discoveredBy
|
gptkb:UCB_Pharma
|
|
gptkbp:drugClass
|
second-generation antihistamine
|
|
gptkbp:eliminationHalfLife
|
8.3 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:hasMolecularFormula
|
C21H25ClN2O3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cetirizine Hydrochloride
|
|
gptkbp:legalStatus
|
OTC (over-the-counter) in many countries
|
|
gptkbp:mechanismOfAction
|
H1 receptor antagonist
|
|
gptkbp:meltingPoint
|
110-115°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:prescriptionStatus
|
prescription or OTC depending on country
|
|
gptkbp:PubChem_CID
|
2678
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
fatigue
headache
drowsiness
dry mouth
|
|
gptkbp:solubility
|
soluble in water
|
|
gptkbp:synonym
|
(±)-Cetirizine hydrochloride
Cetirizine HCl
|
|
gptkbp:UNII
|
YO7261ME24
|
|
gptkbp:usedFor
|
allergic rhinitis
urticaria
|
|
gptkbp:bfsParent
|
gptkb:cetirizine
|
|
gptkbp:bfsLayer
|
6
|