Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
sterol 14α-demethylase family
|
| gptkbp:conservedAcross |
eukaryotes
|
| gptkbp:EC_number |
1.14.14.154
|
| gptkbp:foundIn |
gptkb:Amoebozoa
animals fungi plants |
| gptkbp:function |
catalyzes 14α-demethylation of sterols
|
| gptkbp:geneExample |
CYP51A1
ERG11 |
| gptkbp:GO_term |
GO:0008398 (sterol 14-demethylase activity)
|
| gptkbp:hasBiologicalActivity |
sterol 14-demethylase activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
CYP51 family
|
| gptkbp:InterPro |
IPR001128
|
| gptkbp:involvedIn |
sterol biosynthesis
|
| gptkbp:memberOf |
gptkb:cytochrome_P450_superfamily
|
| gptkbp:mutationAssociatedWith |
azole resistance in fungi
|
| gptkbp:proteinFamily |
PF00067
|
| gptkbp:target |
azole antifungal drugs
|
| gptkbp:UniProtID |
P10614 (yeast ERG11)
P33261 (human CYP51A1) |
| gptkbp:bfsParent |
gptkb:protein
|
| gptkbp:bfsLayer |
4
|