Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
gptkb:GTP
|
| gptkbp:alternativeName |
CTP synthetase
UTP:ammonia ligase (ADP-forming) UTP—ammonia ligase |
| gptkbp:catalyzes |
conversion of UTP to CTP
|
| gptkbp:cofactor |
gptkb:ATP
gptkb:glutamine |
| gptkbp:discoveredBy |
1950s
|
| gptkbp:EC_number |
6.3.4.2
|
| gptkbp:encodedBy |
CTPS1 gene (in humans)
CTPS2 gene (in humans) |
| gptkbp:form |
cytoophidia
|
| gptkbp:foundIn |
gptkb:Bacteria
archaea eukaryotes |
| gptkbp:GO_term |
GO:0003883
|
| gptkbp:has_clinical_relevance |
cancer cell proliferation
immunodeficiency (CTPS1 deficiency) |
| https://www.w3.org/2000/01/rdf-schema#label |
CTP synthase
|
| gptkbp:inhibitedBy |
gptkb:CTP
|
| gptkbp:involves |
pyrimidine biosynthesis
|
| gptkbp:localizes_to |
gptkb:cytoplasm
cytoophidia (filamentous structures) |
| gptkbp:product |
gptkb:CTP
gptkb:ADP phosphate glutamate |
| gptkbp:regulates |
feedback inhibition by CTP
|
| gptkbp:structure |
homotetramer
|
| gptkbp:substrate |
gptkb:UTP
|
| gptkbp:bfsParent |
gptkb:URA7
gptkb:Cytidine_triphosphate |
| gptkbp:bfsLayer |
7
|