Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:associatedWith |
gptkb:Carbamoyl_phosphate_synthetase_I_deficiency
|
| gptkbp:cofactor |
N-acetylglutamate
|
| gptkbp:discoveredBy |
gptkb:Hans_Krebs
|
| gptkbp:discoveredIn |
1960s
|
| gptkbp:EC_number |
6.3.4.16
|
| gptkbp:expressedIn |
gptkb:small_intestine
liver |
| gptkbp:fullName |
gptkb:Carbamoyl_phosphate_synthetase_I
|
| gptkbp:function |
catalyzes the synthesis of carbamoyl phosphate from ammonia and bicarbonate
|
| gptkbp:gene |
gptkb:CPS1_gene
|
| https://www.w3.org/2000/01/rdf-schema#label |
CPS1
|
| gptkbp:locatedOnChromosome |
2q34
|
| gptkbp:location |
mitochondria
|
| gptkbp:molecularWeight |
approximately 165 kDa
|
| gptkbp:mutationAssociatedWith |
hyperammonemia
|
| gptkbp:OMIM |
608307
|
| gptkbp:organism |
humans
|
| gptkbp:pathway |
gptkb:urea_cycle
|
| gptkbp:product |
carbamoyl phosphate
|
| gptkbp:regulates |
activated by N-acetylglutamate
|
| gptkbp:structure |
homotetramer
|
| gptkbp:substrate |
ammonia
bicarbonate |
| gptkbp:UniProtID |
gptkb:P31327
|
| gptkbp:bfsParent |
gptkb:urea_cycle
|
| gptkbp:bfsLayer |
5
|