gptkbp:instanceOf
|
gptkb:protein
|
gptkbp:alternativeName
|
gptkb:thrombospondin-5
|
gptkbp:associatedWith
|
gptkb:pseudoachondroplasia
gptkb:multiple_epiphyseal_dysplasia
osteoarthritis
|
gptkbp:discoveredBy
|
HeinegÄrd D et al.
|
gptkbp:discoveredIn
|
1992
|
gptkbp:encodedBy
|
gptkb:COMP_gene
|
gptkbp:foundIn
|
gptkb:skin
collagen
tendon
vascular smooth muscle
ligament
synovium
|
gptkbp:fullName
|
Cartilage Oligomeric Matrix Protein
|
gptkbp:function
|
structural component of extracellular matrix
interacts with collagen
involved in cartilage development
involved in tissue repair
|
gptkbp:gene
|
gptkb:COMP
|
https://www.w3.org/2000/01/rdf-schema#label
|
COMP protein
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.1
|
gptkbp:memberOf
|
thrombospondin family
|
gptkbp:molecularWeight
|
~524 kDa (pentamer)
|
gptkbp:OMIM
|
600310
|
gptkbp:PDB
|
3FBY
|
gptkbp:postTranslationalModification
|
glycosylation
disulfide bond formation
|
gptkbp:structure
|
pentameric glycoprotein
|
gptkbp:UniProtID
|
P49747
|
gptkbp:usedAs
|
biomarker for joint disease
|
gptkbp:bfsParent
|
gptkb:COMP_gene
|
gptkbp:bfsLayer
|
8
|