Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
hematologic disease
subtype of chronic myelomonocytic leukemia |
| gptkbp:canProgressTo |
gptkb:acute_myeloid_leukemia
|
| gptkbp:definedIn |
World Health Organization classification
|
| gptkbp:distinctiveFeature |
gptkb:CMML-2
|
| gptkbp:hasBlastPercentage |
<10% blasts in bone marrow
<5% blasts in peripheral blood |
| gptkbp:hasCytopenias |
may be present
|
| gptkbp:hasGeneticAbnormalities |
may have ASXL1 mutation
may have SRSF2 mutation may have TET2 mutation |
| gptkbp:hasMonocytosis |
>1x10^9/L monocytes in blood
|
| https://www.w3.org/2000/01/rdf-schema#label |
CMML-1
|
| gptkbp:prognosis |
better than CMML-2
|
| gptkbp:symptom |
gptkb:anemia
fatigue splenomegaly infections |
| gptkbp:treatment |
gptkb:allogeneic_stem_cell_transplantation
supportive care hypomethylating agents |
| gptkbp:bfsParent |
gptkb:CMML
gptkb:chronic_myelomonocytic_leukemia |
| gptkbp:bfsLayer |
7
|