|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:biologicalProcess
|
DNA binding
protein dimerization activity
|
|
gptkbp:encodedBy
|
CLOCK gene
|
|
gptkbp:firstDescribed
|
1997
|
|
gptkbp:formsComplexWith
|
BMAL1 protein
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
transcription factor
regulation of circadian rhythm
|
|
gptkbp:GO_term
|
GO:0005634
GO:0006355
GO:0007623
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CLOCK protein
|
|
gptkbp:interactsWith
|
NPAS2 protein
ARNTL2 protein
|
|
gptkbp:length
|
846 amino acids
|
|
gptkbp:locale
|
gptkb:nucleus
|
|
gptkbp:locatedOnChromosome
|
4q12
|
|
gptkbp:mutationAssociatedWith
|
gptkb:metabolic_syndrome
bipolar disorder
sleep disorders
|
|
gptkbp:OMIM
|
601851
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:regulates
|
CRY1 gene
CRY2 gene
PER1 gene
PER2 gene
|
|
gptkbp:UniProtID
|
O15516
|
|
gptkbp:bfsParent
|
gptkb:CLOCK_(human)
gptkb:CYCLE_protein
gptkb:Circadian_Locomotor_Output_Cycles_Kaput
gptkb:Class_E_basic_helix-loop-helix_protein_2
gptkb:Aryl_hydrocarbon_receptor_nuclear_translocator_like_2
gptkb:E-box
gptkb:Bhlhe41
|
|
gptkbp:bfsLayer
|
8
|