Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
gptkb:CIS
Cytokine-inducible SH2 protein |
| gptkbp:associatedWith |
autoimmune diseases
immune response regulation infectious diseases susceptibility |
| gptkbp:discoveredBy |
1997
|
| gptkbp:domain |
gptkb:SOCS_box
SH2 domain |
| gptkbp:encodes |
Cytokine inducible SH2-containing protein
|
| gptkbp:Entrez_Gene_ID |
1154
ENSG00000163435 |
| gptkbp:expressedIn |
immune cells
|
| gptkbp:function |
negative regulation of cytokine signaling
inhibits JAK-STAT signaling pathway |
| gptkbp:HGNC_ID |
1980
|
| https://www.w3.org/2000/01/rdf-schema#label |
CISH (human gene)
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_3
3p21.3 |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Cish_(mouse_gene)
|
| gptkbp:proteinFamily |
gptkb:SOCS_family
|
| gptkbp:regulates |
interleukin signaling
prolactin signaling erythropoietin signaling |
| gptkbp:UniProtID |
O15524
|
| gptkbp:bfsParent |
gptkb:Cish_(mouse_gene)
|
| gptkbp:bfsLayer |
7
|