Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:T4_antigen
|
| gptkbp:binds |
gptkb:MHC_class_II_molecules
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:CD4_gene
|
| gptkbp:expressedIn |
dendritic cells
macrophages monocytes T helper cells |
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
co-receptor for T cell receptor
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD4 protein
|
| gptkbp:length |
458 amino acids (human)
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_12_(human)
|
| gptkbp:location |
cell surface
|
| gptkbp:molecularWeight |
~55 kDa
|
| gptkbp:OMIM |
186940
|
| gptkbp:PDB |
1WIP
|
| gptkbp:postTranslationalModification |
glycosylation
|
| gptkbp:role |
immune response
|
| gptkbp:significance |
HIV infection monitoring
immunodeficiency diagnosis |
| gptkbp:structure |
single-chain glycoprotein
|
| gptkbp:target |
gptkb:HIV
|
| gptkbp:UniProtID |
P01730
|
| gptkbp:usedAs |
marker for T helper cells
|
| gptkbp:bfsParent |
gptkb:helper_T_cell_(CD4+)
|
| gptkbp:bfsLayer |
7
|