CD146

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs MUC18
MCAM
S-endo
gptkbp:encodedBy MCAM gene
gptkbp:expressedIn gptkb:placenta
smooth muscle
pericytes
some cancer cells
gptkbp:foundIn humans
endothelial cells
melanoma cells
gptkbp:function angiogenesis
cell adhesion
tumor progression
gptkbp:HGNC_ID 6908
https://www.w3.org/2000/01/rdf-schema#label CD146
gptkbp:interactsWith gptkb:laminin
gptkb:VEGF_receptor
galectin-1
gptkbp:locatedOnChromosome 11q23.3
gptkbp:memberOf gptkb:immunoglobulin_superfamily
gptkbp:molecularWeight 113 kDa
gptkbp:OMIM 155735
gptkbp:role cell migration
metastasis
vascular development
gptkbp:structure transmembrane glycoprotein
gptkbp:target therapeutic antibodies
gptkbp:UniProtID P43121
gptkbp:usedAs melanoma marker
gptkbp:bfsParent gptkb:Endothelial_Colony_Forming_Cell
gptkbp:bfsLayer 8