|
gptkbp:instanceOf
|
gptkb:steroid_acid
gptkb:biological_molecule
|
|
gptkbp:actsOn
|
gptkb:farnesoid_X_receptor_(FXR)
G protein-coupled bile acid receptor (TGR5)
|
|
gptkbp:amendedBy
|
intestinal bacteria
|
|
gptkbp:conjugatedWith
|
taurine
glycine
|
|
gptkbp:contains
|
carboxyl group
hydroxyl groups
|
|
gptkbp:derivedFrom
|
cholesterol
|
|
gptkbp:excretion
|
feces
|
|
gptkbp:firstDescribed
|
Heinrich August Ludwig Wiggers
|
|
gptkbp:foundIn
|
bile
|
|
gptkbp:function
|
aid digestion
emulsify fats
facilitate absorption of fat-soluble vitamins
|
|
gptkbp:predecessor
|
bile salts
|
|
gptkbp:producedBy
|
liver
|
|
gptkbp:reabsorbedIn
|
ileum
|
|
gptkbp:regulates
|
cholesterol homeostasis
|
|
gptkbp:secondaryType
|
deoxycholic acid
lithocholic acid
|
|
gptkbp:significance
|
cholestasis
gallstones
malabsorption syndromes
|
|
gptkbp:solubility
|
amphipathic
|
|
gptkbp:structure
|
steroid nucleus
|
|
gptkbp:synthesisType
|
gptkb:hepatocytes
|
|
gptkbp:type
|
gptkb:cholic_acid
chenodeoxycholic acid
|
|
gptkbp:undergo
|
enterohepatic circulation
|
|
gptkbp:usedIn
|
pharmaceuticals
laboratory detergents
|
|
gptkbp:bfsParent
|
gptkb:Bile
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Bile acids
|