Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological molecule
steroid acid |
| gptkbp:actsOn |
gptkb:farnesoid_X_receptor_(FXR)
G protein-coupled bile acid receptor (TGR5) |
| gptkbp:amendedBy |
intestinal bacteria
|
| gptkbp:conjugatedWith |
taurine
glycine |
| gptkbp:contains |
carboxyl group
hydroxyl groups |
| gptkbp:derivedFrom |
cholesterol
|
| gptkbp:excretion |
feces
|
| gptkbp:firstDescribed |
Heinrich August Ludwig Wiggers
|
| gptkbp:foundIn |
bile
|
| gptkbp:function |
aid digestion
emulsify fats facilitate absorption of fat-soluble vitamins |
| https://www.w3.org/2000/01/rdf-schema#label |
Bile acids
|
| gptkbp:predecessor |
bile salts
|
| gptkbp:producedBy |
liver
|
| gptkbp:reabsorbedIn |
ileum
|
| gptkbp:regulates |
cholesterol homeostasis
|
| gptkbp:secondaryType |
deoxycholic acid
lithocholic acid |
| gptkbp:significance |
cholestasis
gallstones malabsorption syndromes |
| gptkbp:solubility |
amphipathic
|
| gptkbp:structure |
steroid nucleus
|
| gptkbp:synthesisType |
gptkb:hepatocytes
|
| gptkbp:type |
gptkb:cholic_acid
chenodeoxycholic acid |
| gptkbp:undergo |
enterohepatic circulation
|
| gptkbp:usedIn |
pharmaceuticals
laboratory detergents |
| gptkbp:bfsParent |
gptkb:Bile
|
| gptkbp:bfsLayer |
7
|