Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antibiotic class
|
| gptkbp:contains |
beta-lactam ring
|
| gptkbp:contraindication |
penicillin allergy
|
| gptkbp:discoveredBy |
gptkb:Alexander_Fleming
|
| gptkbp:excretion |
kidneys
|
| https://www.w3.org/2000/01/rdf-schema#label |
Beta-lactams
|
| gptkbp:includes |
gptkb:cephalosporins
gptkb:monobactams penicillins carbapenems |
| gptkbp:introducedIn |
1940s
|
| gptkbp:mechanismOfAction |
inhibit bacterial cell wall synthesis
|
| gptkbp:metabolism |
liver
|
| gptkbp:resistantTo |
beta-lactamase production
|
| gptkbp:routeOfAdministration |
oral
intramuscular intravenous |
| gptkbp:sideEffect |
allergic reaction
anaphylaxis rash |
| gptkbp:spectrumOfActivity |
broad-spectrum
narrow-spectrum |
| gptkbp:target |
Gram-negative bacteria
Gram-positive bacteria |
| gptkbp:usedFor |
bacterial infections
|
| gptkbp:WHOModelListOfEssentialMedicines |
yes
|
| gptkbp:bfsParent |
gptkb:Antibiotics
|
| gptkbp:bfsLayer |
4
|