Statements (27)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
gptkb:B2M
|
gptkbp:associatedWith |
dialysis-related amyloidosis
|
gptkbp:component |
gptkb:MHC_class_I_molecules
|
gptkbp:degradedBy |
kidneys
|
gptkbp:discoveredIn |
1960s
|
gptkbp:encodedBy |
B2M gene
|
gptkbp:foundIn |
humans
other mammals |
gptkbp:function |
involved in immune response
stabilizes MHC class I molecules |
gptkbp:halfLife |
2-4 hours
|
https://www.w3.org/2000/01/rdf-schema#label |
Beta-2-microglobulin
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_15_(human)
|
gptkbp:molecularWeight |
11.8 kDa
|
gptkbp:OMIM |
109700
|
gptkbp:PDB |
1LDS
|
gptkbp:presentIn |
urine
serum |
gptkbp:significance |
elevated in chronic kidney disease
elevated in multiple myeloma elevated in some lymphomas marker for renal function |
gptkbp:structure |
single polypeptide chain
|
gptkbp:UniProtID |
P61769
|
gptkbp:bfsParent |
gptkb:P0CG47
|
gptkbp:bfsLayer |
7
|