Beta-2-microglobulin

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:B2M
gptkbp:associatedWith dialysis-related amyloidosis
gptkbp:component gptkb:MHC_class_I_molecules
gptkbp:degradedBy kidneys
gptkbp:discoveredIn 1960s
gptkbp:encodedBy B2M gene
gptkbp:foundIn humans
other mammals
gptkbp:function involved in immune response
stabilizes MHC class I molecules
gptkbp:halfLife 2-4 hours
https://www.w3.org/2000/01/rdf-schema#label Beta-2-microglobulin
gptkbp:locatedOnChromosome gptkb:chromosome_15_(human)
gptkbp:molecularWeight 11.8 kDa
gptkbp:OMIM 109700
gptkbp:PDB 1LDS
gptkbp:presentIn urine
serum
gptkbp:significance elevated in chronic kidney disease
elevated in multiple myeloma
elevated in some lymphomas
marker for renal function
gptkbp:structure single polypeptide chain
gptkbp:UniProtID P61769
gptkbp:bfsParent gptkb:P0CG47
gptkbp:bfsLayer 7