BRAF gene fusion in pilocytic astrocytoma
GPTKB entity
Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic alteration
|
| gptkbp:associatedWith |
gptkb:pilocytic_astrocytoma
|
| gptkbp:cause |
oncogenic signaling
|
| gptkbp:commonIn |
pediatric pilocytic astrocytoma
|
| gptkbp:detects |
gptkb:FISH
gptkb:RT-PCR next-generation sequencing |
| gptkbp:firstDescribed |
2008
|
| gptkbp:frequency |
high in pilocytic astrocytoma
|
| https://www.w3.org/2000/01/rdf-schema#label |
BRAF gene fusion in pilocytic astrocytoma
|
| gptkbp:involvedIn |
gptkb:BRAF
KIAA1549 |
| gptkbp:locatedOnChromosome |
gptkb:7q34
|
| gptkbp:notTargetedBy |
BRAF V600E inhibitors
|
| gptkbp:result |
constitutive activation of MAPK pathway
|
| gptkbp:target |
gptkb:MEK_inhibitors
|
| gptkbp:bfsParent |
gptkb:7q34
|
| gptkbp:bfsLayer |
6
|