Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
DNA damage
cellular stress cytokine withdrawal growth factor deprivation |
| gptkbp:describedYear |
1998
|
| gptkbp:discoveredBy |
Stan Korsmeyer
|
| gptkbp:domain |
BH3 domain
|
| gptkbp:example |
gptkb:BAD
gptkb:BMF gptkb:BID gptkb:NOXA gptkb:PUMA gptkb:BIK gptkb:BNIP3 HRK BIM BNIP3L |
| gptkbp:foundIn |
gptkb:metazoans
|
| gptkbp:function |
pro-apoptotic regulator
|
| gptkbp:GO_term |
GO:0006915 (apoptotic process)
GO:0008630 (apoptotic signaling pathway) |
| https://www.w3.org/2000/01/rdf-schema#label |
BH3-only domain protein
|
| gptkbp:interactsWith |
gptkb:anti-apoptotic_Bcl-2_proteins
pro-apoptotic BAK pro-apoptotic BAX |
| gptkbp:involvedIn |
apoptosis
|
| gptkbp:regulates |
mitochondrial outer membrane permeabilization
|
| gptkbp:subclassOf |
Bcl-2 family protein
|
| gptkbp:bfsParent |
gptkb:NOXA
|
| gptkbp:bfsLayer |
7
|