Statements (32)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:drug
                                        
                                         | 
                            
| gptkbp:administeredBy | 
                                    
                                        
                                            
                                            chemotherapy
                                        
                                        
                                         | 
                            
| gptkbp:approvalYear | 
                                    
                                        
                                            
                                            2004
                                        
                                        
                                         | 
                            
| gptkbp:approvedBy | 
                                    
                                        
                                            gptkb:FDA
                                        
                                         | 
                            
| gptkbp:ATCCode | 
                                    
                                        
                                            
                                            L01XC07
                                        
                                        
                                         | 
                            
| gptkbp:biosimilar | 
                                    
                                        
                                            
                                            yes
                                        
                                        
                                         | 
                            
| gptkbp:blackBoxWarning | 
                                    
                                        
                                            
                                            yes
                                        
                                        
                                         | 
                            
| gptkbp:CASNumber | 
                                    
                                        
                                            
                                            216974-75-3
                                        
                                        
                                         | 
                            
| gptkbp:contraindication | 
                                    
                                        
                                            
                                            hypersensitivity to bevacizumab
                                        
                                        
                                         | 
                            
| gptkbp:developedBy | 
                                    
                                        
                                            gptkb:Genentech
                                        
                                         | 
                            
| gptkbp:genericName | 
                                    
                                        
                                            gptkb:bevacizumab
                                        
                                         | 
                            
| gptkbp:hasMolecularFormula | 
                                    
                                        
                                            
                                            C6638H10160N1720O2104S44
                                        
                                        
                                         | 
                            
| gptkbp:legalStatus | 
                                    
                                        
                                            
                                            prescription only
                                        
                                        
                                         | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            
                                            VEGF inhibitor
                                        
                                        
                                         | 
                            
| gptkbp:monoclonalAntibodyType | 
                                    
                                        
                                            
                                            humanized
                                        
                                        
                                         | 
                            
| gptkbp:patentExpired | 
                                    
                                        
                                            
                                            2019
                                        
                                        
                                         | 
                            
| gptkbp:pregnancyCategory | 
                                    
                                        
                                            
                                            D (US)
                                        
                                        
                                         | 
                            
| gptkbp:PubChem_CID | 
                                    
                                        
                                            
                                            DB00112
                                        
                                        
                                         | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            intravenous
                                        
                                        
                                         | 
                            
| gptkbp:sideEffect | 
                                    
                                        
                                            
                                            bleeding
                                        
                                        
                                         hypertension proteinuria gastrointestinal perforation  | 
                            
| gptkbp:UNII | 
                                    
                                        
                                            
                                            82F0S815PN
                                        
                                        
                                         | 
                            
| gptkbp:usedFor | 
                                    
                                        
                                            gptkb:non-small_cell_lung_cancer
                                        
                                         gptkb:cancer gptkb:renal_cell_carcinoma gptkb:glioblastoma colorectal cancer  | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:Genentech
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            5
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            Avastin
                                        
                                        
                                         |