Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:SGOT
AST |
| gptkbp:CASNumber |
9000-97-9
|
| gptkbp:catalyzes |
transamination of aspartate and α-ketoglutarate
|
| gptkbp:clinical_use |
marker for myocardial infarction
marker for liver damage |
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
2.6.1.1
|
| gptkbp:firstDescribed |
1955
|
| gptkbp:foundIn |
gptkb:skeletal_muscle
gptkb:kidney brain heart liver |
| gptkbp:gene |
gptkb:GOT1
gptkb:GOT2 |
| https://www.w3.org/2000/01/rdf-schema#label |
Aspartate transaminase
|
| gptkbp:inhibitedBy |
gptkb:aminooxyacetate
|
| gptkbp:involves |
gptkb:urea_cycle
amino acid metabolism |
| gptkbp:measures |
blood test
|
| gptkbp:molecularWeight |
~45 kDa per subunit
|
| gptkbp:optimum_pH |
7.4
|
| gptkbp:PDB |
gptkb:1AJS
|
| gptkbp:product |
gptkb:oxaloacetate
glutamate |
| gptkbp:structure |
homodimer
|
| gptkbp:subcellularLocation |
gptkb:cytoplasm
mitochondria |
| gptkbp:UniProtID |
P17174
|
| gptkbp:bfsParent |
gptkb:Transaminase
|
| gptkbp:bfsLayer |
7
|