Arestin

GPTKB entity

Statements (54)
Predicate Object
gptkbp:instance_of gptkb:pharmaceuticals
gptkbp:class Tetracycline antibiotic
gptkbp:clinical_trial Phase III
Long-term effects study
Comparative study with placebo
Study on efficacy
Study on safety
gptkbp:clinical_use Periodontal pockets
gptkbp:contraindication Pregnancy
Lactation
Hypersensitivity to minocycline
gptkbp:dosage_form Powder for oral suspension
gptkbp:duration Up to 6 months
gptkbp:effective_date 2001-06-29
gptkbp:formulation Microspheres
https://www.w3.org/2000/01/rdf-schema#label Arestin
gptkbp:indication Adjunct to scaling and root planing
gptkbp:ingredients gptkb:Minocycline
gptkbp:manufacturer gptkb:Ora_Pharma,_Inc.
gptkbp:marketed_as gptkb:Canada
gptkb:European_Union
gptkb:United_States
gptkbp:mechanism_of_action Antimicrobial
gptkbp:packaging Single-use applicator
gptkbp:patient_population Adults
Adolescents
gptkbp:pharmacokinetics Localized delivery
gptkbp:regulatory_compliance FDA approved
EMA approved
Health Canada approved
gptkbp:requires gptkb:True
gptkbp:research Cost-effectiveness analysis
Patient satisfaction survey
Effectiveness in chronic periodontitis
Impact on microbiome
Long-term safety profile
gptkbp:route_of_administration Local delivery
gptkbp:service_frequency Once per treatment site
gptkbp:side_effect gptkb:Nausea
Diarrhea
Dizziness
Headache
Skin rash
Oral mucosal ulceration
Taste disturbance
Vaginal candidiasis
gptkbp:storage Room temperature
gptkbp:treatment Improvement in clinical attachment level
Reduction in bleeding on probing
Improvement in oral health
Reduction in pocket depth
gptkbp:used_for Periodontal disease
gptkbp:bfsParent gptkb:Valeant_Pharmaceuticals
gptkbp:bfsLayer 6