Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
antiviral drug
antineoplastic agent |
gptkbp:administeredBy |
subcutaneous injection
intravenous injection intrathecal injection |
gptkbp:affiliatedWith |
antineoplastic agent
|
gptkbp:approvedBy |
gptkb:FDA
|
gptkbp:ATCCode |
L01BC01
|
gptkbp:brand |
gptkb:Depocyt
Cytosar |
gptkbp:CASNumber |
147-94-4
|
gptkbp:chemicalClass |
gptkb:cytarabine
|
gptkbp:contraindication |
hypersensitivity to cytarabine
|
gptkbp:discoveredIn |
1960s
|
gptkbp:eliminatedIn |
renal
|
gptkbp:hasMolecularFormula |
C9H13N3O5
|
https://www.w3.org/2000/01/rdf-schema#label |
Ara-C
|
gptkbp:mechanismOfAction |
inhibits DNA synthesis
|
gptkbp:metabolism |
liver
|
gptkbp:pregnancyCategory |
D (US)
|
gptkbp:sideEffect |
fever
nausea vomiting diarrhea neurotoxicity myelosuppression |
gptkbp:synonym |
gptkb:Cytosar-U
cytosine arabinoside |
gptkbp:usedFor |
treatment of acute lymphoblastic leukemia
treatment of acute myeloid leukemia treatment of non-Hodgkin lymphoma |
gptkbp:bfsParent |
gptkb:cytarabine
|
gptkbp:bfsLayer |
7
|