|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:ANK
|
|
gptkbp:binds
|
gptkb:L1CAM
gptkb:E-cadherin
gptkb:Na+/K+_ATPase
ion channels
cell adhesion molecules
voltage-gated sodium channels
spectrin
band 3 protein
|
|
gptkbp:discoveredBy
|
gptkb:Vann_Bennett
|
|
gptkbp:domain
|
ankyrin repeat
|
|
gptkbp:encodedBy
|
gptkb:ANK2
gptkb:ANK1
gptkb:ANK3
|
|
gptkbp:firstDescribed
|
1979
|
|
gptkbp:foundIn
|
animals
|
|
gptkbp:function
|
links integral membrane proteins to the spectrin-actin cytoskeleton
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ankyrin
|
|
gptkbp:involvedIn
|
signal transduction
cellular organization
membrane stability
|
|
gptkbp:locale
|
gptkb:plasma_membrane
erythrocyte membrane
neuronal axon initial segment
|
|
gptkbp:mutationAssociatedWith
|
gptkb:hereditary_spherocytosis
gptkb:arrhythmia
neurological disorders
|
|
gptkbp:OMIM
|
106410
|
|
gptkbp:proteinFamily
|
gptkb:ANK2
gptkb:ANK1
gptkb:ANK3
|
|
gptkbp:relatedTo
|
neuronal development
cell polarity
actin cytoskeleton
cardiac conduction
spectrin
erythrocyte stability
membrane skeleton
|
|
gptkbp:subspecies
|
gptkb:ankyrin-B
ankyrin-G
ankyrin-R
|
|
gptkbp:UniProtID
|
P16157
|
|
gptkbp:bfsParent
|
gptkb:Red_Blood_Cells
|
|
gptkbp:bfsLayer
|
8
|