|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:approvalYear
|
1972
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
J01CA04
|
|
gptkbp:bioavailability
|
95%
|
|
gptkbp:brand
|
gptkb:Amoxil
gptkb:Moxatag
gptkb:Trimox
|
|
gptkbp:CASNumber
|
26787-78-0
|
|
gptkbp:category
|
gptkb:drug
antibacterial
|
|
gptkbp:chemicalFormula
|
C16H19N3O5S
|
|
gptkbp:combines
|
gptkb:clavulanic_acid
|
|
gptkbp:contraindication
|
penicillin allergy
|
|
gptkbp:discoveredBy
|
gptkb:Beecham_Group
|
|
gptkbp:eliminationHalfLife
|
1-1.5 hours
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Amoxicillin
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial cell wall synthesis
|
|
gptkbp:meltingPoint
|
194–196 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
365.4 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:proteinBinding
|
17–20%
|
|
gptkbp:PubChem_CID
|
33613
DB01060
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
allergic reaction
rash
|
|
gptkbp:solubility
|
3.4 mg/mL
|
|
gptkbp:spectrumOfActivity
|
broad-spectrum
|
|
gptkbp:UNII
|
9EM05410Q9
|
|
gptkbp:usedFor
|
gptkb:sinusitis
gptkb:pneumonia
skin infections
urinary tract infections
bacterial infections
otitis media
strep throat
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:Antibiotics
|
|
gptkbp:bfsLayer
|
4
|