Statements (53)
Predicate | Object |
---|---|
gptkbp:instanceOf |
benzodiazepine
sedative-hypnotic drug |
gptkbp:ATCCode |
N05CA03
|
gptkbp:brand |
Amytal
|
gptkbp:CASNumber |
57-43-2
|
gptkbp:category |
benzodiazepine
anticonvulsant hypnotic barbiturate derivative GABA_A receptor positive allosteric modulator barbiturate sedative World Health Organization essential medicine (historical) |
gptkbp:chemicalFormula |
C11H18N2O3
|
gptkbp:color |
white
|
gptkbp:contraindication |
porphyria
severe respiratory insufficiency history of addiction |
gptkbp:discoveredBy |
Augustus Desire Waller
|
gptkbp:eliminationHalfLife |
8–42 hours
|
https://www.w3.org/2000/01/rdf-schema#label |
Amobarbital
|
gptkbp:introducedIn |
1923
|
gptkbp:IUPACName |
5-ethyl-5-(3-methylbutyl)barbituric acid
|
gptkbp:legalStatus |
gptkb:Schedule_II_controlled_substance
|
gptkbp:metabolism |
liver
|
gptkbp:molecularWeight |
226.27 g/mol
|
gptkbp:notRecommendedFor |
elderly
long-term use |
gptkbp:pregnancyCategory |
D
|
gptkbp:produces_effect |
sedation
central nervous system depression sleep induction |
gptkbp:PubChem_CID |
2075
2161 CHEMBL1201192 |
gptkbp:riskFactor |
addiction
overdose withdrawal symptoms |
gptkbp:routeOfAdministration |
oral
intramuscular intravenous |
gptkbp:sideEffect |
drowsiness
respiratory depression dependence |
gptkbp:solubility |
slightly soluble
|
gptkbp:synonym |
Amytal sodium
amylobarbitone amylobarbituric acid |
gptkbp:UNII |
G15YON7B6B
|
gptkbp:usedFor |
sedation
treatment of insomnia preanesthetic |
gptkbp:bfsParent |
gptkb:Barbiturates
|
gptkbp:bfsLayer |
7
|