Amobarbital

GPTKB entity

Statements (53)
Predicate Object
gptkbp:instanceOf benzodiazepine
sedative-hypnotic drug
gptkbp:ATCCode N05CA03
gptkbp:brand Amytal
gptkbp:CASNumber 57-43-2
gptkbp:category benzodiazepine
anticonvulsant
hypnotic
barbiturate derivative
GABA_A receptor positive allosteric modulator
barbiturate sedative
World Health Organization essential medicine (historical)
gptkbp:chemicalFormula C11H18N2O3
gptkbp:color white
gptkbp:contraindication porphyria
severe respiratory insufficiency
history of addiction
gptkbp:discoveredBy Augustus Desire Waller
gptkbp:eliminationHalfLife 8–42 hours
https://www.w3.org/2000/01/rdf-schema#label Amobarbital
gptkbp:introducedIn 1923
gptkbp:IUPACName 5-ethyl-5-(3-methylbutyl)barbituric acid
gptkbp:legalStatus gptkb:Schedule_II_controlled_substance
gptkbp:metabolism liver
gptkbp:molecularWeight 226.27 g/mol
gptkbp:notRecommendedFor elderly
long-term use
gptkbp:pregnancyCategory D
gptkbp:produces_effect sedation
central nervous system depression
sleep induction
gptkbp:PubChem_CID 2075
2161
CHEMBL1201192
gptkbp:riskFactor addiction
overdose
withdrawal symptoms
gptkbp:routeOfAdministration oral
intramuscular
intravenous
gptkbp:sideEffect drowsiness
respiratory depression
dependence
gptkbp:solubility slightly soluble
gptkbp:synonym Amytal sodium
amylobarbitone
amylobarbituric acid
gptkbp:UNII G15YON7B6B
gptkbp:usedFor sedation
treatment of insomnia
preanesthetic
gptkbp:bfsParent gptkb:Barbiturates
gptkbp:bfsLayer 7