|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:fructose-bisphosphate_aldolase_B
gptkb:liver-type_aldolase
|
|
gptkbp:associatedWith
|
gptkb:hereditary_fructose_intolerance
|
|
gptkbp:catalyzes
|
fructose-1,6-bisphosphate to dihydroxyacetone phosphate and glyceraldehyde-3-phosphate
fructose-1-phosphate to dihydroxyacetone phosphate and glyceraldehyde
|
|
gptkbp:cofactor
|
none required
|
|
gptkbp:EC_number
|
4.1.2.13
|
|
gptkbp:enzymeClassification
|
lyase
|
|
gptkbp:expressedIn
|
gptkb:hepatocytes
renal cortex
enterocytes
|
|
gptkbp:family
|
gptkb:aldolase_family
|
|
gptkbp:foundIn
|
gptkb:kidney
gptkb:small_intestine
liver
|
|
gptkbp:gene
|
gptkb:ALDOB
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Aldolase B
|
|
gptkbp:inhibitedBy
|
fructose-1-phosphate (at high concentrations)
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_9q22.3
|
|
gptkbp:molecularWeight
|
about 36 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:hereditary_fructose_intolerance
|
|
gptkbp:OMIM
|
612724
|
|
gptkbp:pathway
|
glycolysis
gluconeogenesis
fructose metabolism
|
|
gptkbp:PDB
|
1QO5
|
|
gptkbp:product
|
glyceraldehyde-3-phosphate
glyceraldehyde
dihydroxyacetone phosphate
|
|
gptkbp:structure
|
homotetramer
|
|
gptkbp:substrate
|
fructose-1,6-bisphosphate
fructose-1-phosphate
|
|
gptkbp:UniProtID
|
P05062
|
|
gptkbp:bfsParent
|
gptkb:Aldolase
|
|
gptkbp:bfsLayer
|
7
|