Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:abbreviation |
gptkb:ALT
gptkb:SGPT |
| gptkbp:CASNumber |
9000-86-6
|
| gptkbp:catalyzes |
transamination of alanine and α-ketoglutarate to pyruvate and glutamate
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:decreasedIn |
gptkb:vitamin_B6_deficiency
|
| gptkbp:discoveredBy |
1955
|
| gptkbp:EC_number |
2.6.1.2
|
| gptkbp:foundIn |
gptkb:skeletal_muscle
gptkb:kidney heart liver |
| gptkbp:gene |
gptkb:GPT
|
| gptkbp:GO_term |
GO:0004021
|
| gptkbp:increased_in |
myocardial infarction
hepatitis liver cirrhosis muscle injury |
| gptkbp:measured_in_units |
U/L
|
| gptkbp:measures |
blood tests
|
| gptkbp:molecularWeight |
approximately 55 kDa
|
| gptkbp:normal_range_(adults) |
7-56 U/L
|
| gptkbp:product |
gptkb:pyruvate
gptkb:L-glutamate |
| gptkbp:structure |
homodimer
|
| gptkbp:substrate |
gptkb:α-ketoglutarate
L-alanine |
| gptkbp:UniProtID |
gptkb:P24298
|
| gptkbp:used_to_diagnose |
liver damage
|
| gptkbp:bfsParent |
gptkb:Transaminase
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Alanine transaminase
|