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gptkbp:instanceOf
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gptkb:enzyme
|
|
gptkbp:abbreviation
|
gptkb:ALT
gptkb:SGPT
|
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gptkbp:CASNumber
|
9000-86-6
|
|
gptkbp:catalyzes
|
transamination of alanine and α-ketoglutarate to pyruvate and glutamate
|
|
gptkbp:cofactor
|
gptkb:pyridoxal_phosphate
|
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gptkbp:decreasedIn
|
gptkb:vitamin_B6_deficiency
|
|
gptkbp:discoveredBy
|
1955
|
|
gptkbp:EC_number
|
2.6.1.2
|
|
gptkbp:foundIn
|
gptkb:skeletal_muscle
gptkb:kidney
heart
liver
|
|
gptkbp:gene
|
gptkb:GPT
|
|
gptkbp:GO_term
|
GO:0004021
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Alanine transaminase
|
|
gptkbp:increased_in
|
myocardial infarction
hepatitis
liver cirrhosis
muscle injury
|
|
gptkbp:measured_in_units
|
U/L
|
|
gptkbp:measures
|
blood tests
|
|
gptkbp:molecularWeight
|
approximately 55 kDa
|
|
gptkbp:normal_range_(adults)
|
7-56 U/L
|
|
gptkbp:product
|
gptkb:pyruvate
gptkb:L-glutamate
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:α-ketoglutarate
L-alanine
|
|
gptkbp:UniProtID
|
gptkb:P24298
|
|
gptkbp:used_to_diagnose
|
liver damage
|
|
gptkbp:bfsParent
|
gptkb:Transaminase
gptkb:Transferase
|
|
gptkbp:bfsLayer
|
7
|