Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
adrenodoxin-NADP+ reductase
ferredoxin--NADP(+) reductase (mitochondrial) |
| gptkbp:associatedWith |
mitochondrial disease
adrenal insufficiency |
| gptkbp:cofactor |
gptkb:FAD
NADPH |
| gptkbp:discoveredBy |
1960s
|
| gptkbp:EC_number |
1.18.1.6
|
| gptkbp:foundIn |
mitochondria
|
| gptkbp:function |
catalyzes electron transfer from NADPH to adrenodoxin
|
| gptkbp:gene |
gptkb:FDXR
|
| https://www.w3.org/2000/01/rdf-schema#label |
Adrenodoxin Reductase
|
| gptkbp:involves |
steroid biosynthesis
|
| gptkbp:locatedIn |
inner mitochondrial membrane
|
| gptkbp:locatedOnChromosome |
chromosome 17q24.2
|
| gptkbp:molecularWeight |
about 54 kDa
|
| gptkbp:OMIM |
103270
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
Mus musculus Fdxr
Rattus norvegicus Fdxr |
| gptkbp:PDB |
1E6E
|
| gptkbp:product |
NADP+
reduced adrenodoxin |
| gptkbp:requires |
biosynthesis of glucocorticoids
biosynthesis of mineralocorticoids biosynthesis of sex steroids |
| gptkbp:structure |
monomeric protein
|
| gptkbp:substrate |
NADPH
adrenodoxin |
| gptkbp:UniProtID |
P22570
|
| gptkbp:bfsParent |
gptkb:AADR
|
| gptkbp:bfsLayer |
7
|