Adeno-associated virus (AAV) vectors
GPTKB entity
Properties (60)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
viral vector
|
| gptkbp:built |
gptkb:Adeno-associated_virus
|
| gptkbp:canBe |
large transgenes
|
| gptkbp:characterizedBy |
non-pathogenicity
|
| gptkbp:hasFestival |
true
|
| gptkbp:hasRelatedPatent |
eye diseases
liver diseases metabolic disorders neurodegenerative diseases rare diseases autoimmune diseases chronic diseases chronic pain vaccination sleep disorders anxiety disorders mental health disorders cardiovascular diseases infectious diseases lung diseases substance use disorders eating disorders developmental disorders mood disorders personality disorders cognitive disorders kidney diseases inflammatory diseases neurodevelopmental disorders muscle disorders endocrine disorders acute diseases treatment of infectious diseases pediatric diseases neuropsychiatric disorders psychotic disorders skin disorders treatment of genetic disorders common diseases behavioral disorders sexual disorders geriatric_diseases |
| gptkbp:hasVariants |
gptkb:AAV9
gptkb:AAV8 AAV1 AAV2 AAV5 |
| https://www.w3.org/2000/01/rdf-schema#label |
Adeno-associated virus (AAV) vectors
|
| gptkbp:is_used_in |
clinical trials
|
| gptkbp:isIntegratedWith |
into host genome
|
| gptkbp:producedBy |
recombinant DNA technology
|
| gptkbp:requires |
helper virus for replication
|
| gptkbp:suitableFor |
transducing dividing and non-dividing cells
|
| gptkbp:usedFor |
gene therapy
|
| gptkbp:usedIn |
cancer therapy
muscular dystrophy hemophilia neurological disorders cystic fibrosis retinal diseases |