Actilyse

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:activeIngredient gptkb:alteplase
gptkbp:approvedBy 1987
gptkbp:ATCCode B01AD02
gptkbp:CASNumber 105857-23-6
gptkbp:contraindication active internal bleeding
severe uncontrolled hypertension
history of hemorrhagic stroke
gptkbp:form powder for solution for injection
https://www.w3.org/2000/01/rdf-schema#label Actilyse
gptkbp:legalStatus prescription only
gptkbp:manufacturer gptkb:Boehringer_Ingelheim
gptkbp:mechanismOfAction gptkb:tissue_plasminogen_activator
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect bleeding
intracranial hemorrhage
gptkbp:status approved by FDA
approved by EMA
gptkbp:usedFor myocardial infarction
pulmonary embolism
acute ischemic stroke
gptkbp:bfsParent gptkb:alteplase
gptkbp:bfsLayer 7