Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:CRISPR-Cas_system
|
| gptkbp:affiliatedWith |
gptkb:Type_V_CRISPR_system
Class 2 CRISPR system |
| gptkbp:alsoKnownAs |
gptkb:Cpf1
|
| gptkbp:cleavage |
double-stranded DNA
staggered cut |
| gptkbp:compatibleWith |
gptkb:tracrRNA
|
| gptkbp:discoveredIn |
gptkb:Acidaminococcus_sp._BV3L6
|
| gptkbp:firstDescribed |
2015
|
| gptkbp:function |
gptkb:DNA_endonuclease
Genome editing |
| https://www.w3.org/2000/01/rdf-schema#label |
Acidaminococcus sp. Cas12a
|
| gptkbp:notableFor |
collateral cleavage activity
simpler guide RNA structure |
| gptkbp:recognizesPAM |
TTTV
|
| gptkbp:requires |
gptkb:crRNA
|
| gptkbp:usedBy |
Bacterial genome editing
Mammalian genome editing Plant genome editing |
| gptkbp:usedIn |
CRISPR gene editing
Diagnostics |
| gptkbp:bfsParent |
gptkb:Cas12_family
|
| gptkbp:bfsLayer |
8
|