|
gptkbp:instanceOf
|
gptkb:drug
analgesic
Antipyretic
|
|
gptkbp:approvedBy
|
gptkb:Canada
gptkb:United_Kingdom
gptkb:United_States
|
|
gptkbp:ATCCode
|
N02BE01
|
|
gptkbp:availableOn
|
gptkb:tablet
gptkb:water
Capsule
Intravenous solution
Suppository
|
|
gptkbp:boilingPoint
|
420°C
|
|
gptkbp:brand
|
gptkb:Tylenol
gptkb:Panadol
gptkb:Ofirmev
Mapap
|
|
gptkbp:CASNumber
|
103-90-2
|
|
gptkbp:chemicalFormula
|
C8H9NO2
|
|
gptkbp:contraindication
|
Severe liver disease
Hypersensitivity
|
|
gptkbp:discoveredBy
|
gptkb:Harmon_Northrop_Morse
|
|
gptkbp:discoveredIn
|
1877
|
|
gptkbp:excretion
|
gptkb:Kidneys
|
|
gptkbp:hasUNII
|
362O9ITL9D
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Acetaminophen
|
|
gptkbp:includedIn
|
gptkb:WHO_Model_List_of_Essential_Medicines
|
|
gptkbp:isPrescriptionRequired
|
No (in most countries)
|
|
gptkbp:IUPACName
|
N-(4-hydroxyphenyl)acetamide
|
|
gptkbp:KEGGID
|
D00217
|
|
gptkbp:legalStatus
|
gptkb:OTC
|
|
gptkbp:legalStatusAU
|
gptkb:OTC
|
|
gptkbp:legalStatusUK
|
gptkb:OTC
|
|
gptkbp:marketedAs
|
1950s
|
|
gptkbp:maximumDailyDoseAdult
|
4000 mg
|
|
gptkbp:mechanismOfAction
|
Inhibits prostaglandin synthesis
|
|
gptkbp:meltingPoint
|
169°C
|
|
gptkbp:metabolism
|
Liver
|
|
gptkbp:molecularWeight
|
151.16 g/mol
|
|
gptkbp:otherName
|
gptkb:APAP
gptkb:Paracetamol
|
|
gptkbp:pregnancyCategory
|
C
|
|
gptkbp:PubChem_CID
|
1983
DB00316
46195
|
|
gptkbp:routeOfAdministration
|
gptkb:Oral
Rectal
Intravenous
|
|
gptkbp:sideEffect
|
Allergic reaction
Liver damage (in overdose)
|
|
gptkbp:usedFor
|
Fever reduction
Pain relief
|
|
gptkbp:bfsParent
|
gptkb:paracetamol
|
|
gptkbp:bfsLayer
|
6
|