|
gptkbp:instanceOf
|
gptkb:drug
abbreviation
|
|
gptkbp:affiliatedWith
|
analgesics
antipyretics
|
|
gptkbp:alsoKnownAs
|
gptkb:paracetamol
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
N02BE01
|
|
gptkbp:availableInForm
|
gptkb:tablet
gptkb:water
capsule
suppository
|
|
gptkbp:availableOn
|
over-the-counter medication
|
|
gptkbp:bioavailability
|
63–89% (oral)
|
|
gptkbp:CASNumber
|
103-90-2
|
|
gptkbp:cause
|
liver toxicity (in overdose)
|
|
gptkbp:chemicalFormula
|
C8H9NO2
|
|
gptkbp:combines
|
gptkb:NSAIDs
opioids
caffeine
|
|
gptkbp:contraindication
|
severe liver disease
|
|
gptkbp:discoveredBy
|
gptkb:Harmon_Northrop_Morse
|
|
gptkbp:discoveredIn
|
1877
|
|
gptkbp:eliminationHalfLife
|
1–4 hours
|
|
gptkbp:excretion
|
kidneys
|
|
gptkbp:halfLife
|
1–4 hours
|
|
gptkbp:hasInChIKey
|
gptkb:RZVAJINKPMORJF-UHFFFAOYSA-N
|
|
gptkbp:hasSMILES
|
CC(=O)NC1=CC=C(C=C1)O
|
|
gptkbp:hasUNII
|
362O9ITL9D
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
APAP
|
|
gptkbp:includedIn
|
gptkb:WHO_Model_List_of_Essential_Medicines
|
|
gptkbp:IUPACName
|
N-(4-hydroxyphenyl)acetamide
|
|
gptkbp:KEGGID
|
D00217
|
|
gptkbp:legalStatus
|
OTC (over-the-counter) in most countries
|
|
gptkbp:meltingPoint
|
169°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
151.16 g/mol
|
|
gptkbp:pregnancyCategory
|
generally considered safe
|
|
gptkbp:proteinBinding
|
10–25%
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL112
1906
1983
DB00316
|
|
gptkbp:sideEffect
|
nausea
allergic reaction
rash
|
|
gptkbp:soldUnderBrandName
|
gptkb:Tylenol
gptkb:Panadol
|
|
gptkbp:standsFor
|
acetaminophen
|
|
gptkbp:usedFor
|
pain relief
fever reduction
|
|
gptkbp:bfsParent
|
gptkb:GVGLGOZIDCSQPN-UHFFFAOYSA-N
gptkb:Acetaminophen
gptkb:XSQUKJJJFZCRTK-UHFFFAOYSA-N
gptkb:Paraguayan_American_Friendship_Association
|
|
gptkbp:bfsLayer
|
7
|