|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:bfsLayer
|
4
|
|
gptkbp:bfsParent
|
gptkb:Burroughs_Wellcome
|
|
gptkbp:activities
|
gptkb:nucleoside_reverse_transcriptase_inhibitor
|
|
gptkbp:appointed_by
|
oral tablet
|
|
gptkbp:approves
|
gptkb:FDA
|
|
gptkbp:brand
|
gptkb:Ziagen
|
|
gptkbp:can_be_used_with
|
gptkb:lamivudine
gptkb:zidovudine
|
|
gptkbp:clinical_trial
|
Phase III
|
|
gptkbp:contraindication
|
gptkb:HLA-B*5701_allele
severe liver disease
|
|
gptkbp:discovered_by
|
gptkb:1998
|
|
gptkbp:dosage_form
|
300 mg once daily
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Abacavir
|
|
gptkbp:ingredients
|
C14 H18 N6 O
|
|
gptkbp:interacts_with
|
gptkb:beer
|
|
gptkbp:is_atype_of
|
J05 A F01
|
|
gptkbp:is_available_on
|
generic drug
|
|
gptkbp:is_monitored_by
|
liver function tests
viral load
C D4 count
|
|
gptkbp:is_used_for
|
treatment of HIV
|
|
gptkbp:lifespan
|
1.5 hours
|
|
gptkbp:manager
|
oral
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pharmacokinetics
|
bioavailability 83%
|
|
gptkbp:side_effect
|
fatigue
headache
nausea
diarrhea
rash
hypersensitivity reaction
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:type_of
|
136470-78-5
|