Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
combination drug
|
| gptkbp:alternativeTo |
gptkb:ATRA_plus_chemotherapy
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:component |
gptkb:all-trans_retinoic_acid
gptkb:arsenic_trioxide |
| https://www.w3.org/2000/01/rdf-schema#label |
ATRA plus arsenic trioxide
|
| gptkbp:mechanismOfAction |
induces apoptosis of leukemic cells
induces differentiation of promyelocytes |
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
QT prolongation
hepatotoxicity leukocytosis differentiation syndrome |
| gptkbp:standardOfCareFor |
newly diagnosed acute promyelocytic leukemia
|
| gptkbp:usedFor |
gptkb:acute_promyelocytic_leukemia
|
| gptkbp:bfsParent |
gptkb:acute_promyelocytic_leukemia
|
| gptkbp:bfsLayer |
6
|