ATP-binding cassette sub-family G member 1

URI: https://gptkb.org/entity/ATP-binding_cassette_sub-family_G_member_1
GPTKB entity
Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:ABC8
white
ATP-binding cassette transporter 8
gptkbp:associatedWith atherosclerosis
lipid homeostasis
gptkbp:encodedBy ABCG1 gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000160179
9619
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function cholesterol and phospholipid transport
gptkbp:gene gptkb:ABCG1
https://www.w3.org/2000/01/rdf-schema#label ATP-binding cassette sub-family G member 1
gptkbp:locatedOnChromosome 21q22.3
gptkbp:location gptkb:plasma_membrane
intracellular membranes
gptkbp:member gptkb:ATP-binding_cassette_transporter_family
sub-family G
gptkbp:orthologInMouse gptkb:Abcg1
gptkbp:regulates regulated by oxysterols
upregulated by LXR activation
gptkbp:relatedTo reverse cholesterol transport
gptkbp:structure contains two nucleotide-binding domains
contains two transmembrane domains
gptkbp:transportation cholesterol
phospholipids
gptkbp:UniProtID Q9H222
gptkbp:vehicleType full transporter
gptkbp:bfsParent gptkb:ABCG1
gptkbp:bfsLayer 7