|
gptkbp:instance_of
|
gptkb:pharmaceuticals
|
|
gptkbp:advocacy
|
required
|
|
gptkbp:can_be_combined_with
|
chemotherapy
|
|
gptkbp:class
|
gptkb:immunotherapy
|
|
gptkbp:clinical_trial
|
gptkb:United_States
gptkb:Apexigen
Phase 2
not yet published
open-label
NCT number
|
|
gptkbp:clinical_trial_phase1_results
|
not disclosed
|
|
gptkbp:clinical_trial_phase2_results
|
not disclosed
|
|
gptkbp:clinical_trial_results_publication
|
anticipated
|
|
gptkbp:collaborations
|
academic institutions
|
|
gptkbp:committee
|
established
|
|
gptkbp:criteria
|
adult patients
prior anti-CD40 therapy
|
|
gptkbp:developed_by
|
gptkb:Apexigen
|
|
gptkbp:dosage_form
|
to be defined
|
|
gptkbp:duration
|
up to 12 months
|
|
gptkbp:eligibility
|
ongoing
|
|
gptkbp:events
|
6 months
|
|
gptkbp:finale_date
|
overall response rate
progression-free survival
|
|
gptkbp:funding
|
secured
|
|
gptkbp:healthcare
|
yes
pending
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
APX005 M
|
|
gptkbp:indication
|
gptkb:Oncology
|
|
gptkbp:invention
|
patented
|
|
gptkbp:investigates
|
active
clinical researchers
|
|
gptkbp:is_effective_against
|
under evaluation
|
|
gptkbp:is_tested_for
|
Phase 1
CD40 expression
|
|
gptkbp:market_position
|
not available
|
|
gptkbp:mechanism_of_action
|
immune checkpoint inhibitor
|
|
gptkbp:patient_population
|
adults
|
|
gptkbp:project
|
early stage
|
|
gptkbp:publication
|
forthcoming
|
|
gptkbp:regulatory_compliance
|
under review
|
|
gptkbp:related_products
|
submitted
|
|
gptkbp:research
|
completed
|
|
gptkbp:research_areas
|
oncology
|
|
gptkbp:research_ethics_approval
|
obtained
|
|
gptkbp:research_focus
|
solid tumors
|
|
gptkbp:route_of_administration
|
intravenous
|
|
gptkbp:safety_features
|
under investigation
|
|
gptkbp:safety_measures
|
ongoing
|
|
gptkbp:service_frequency
|
every 2 weeks
|
|
gptkbp:side_effect
|
to be determined
|
|
gptkbp:sponsor
|
gptkb:biotechnology
|
|
gptkbp:status
|
gptkb:Clinical_Trials
|
|
gptkbp:targets
|
gptkb:CD40
|
|
gptkbp:treatment
|
monotherapy
|
|
gptkbp:bfsParent
|
gptkb:Apexigen
|
|
gptkbp:bfsLayer
|
5
|