Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:A_Proliferation-Inducing_Ligand
gptkb:TNFSF13 |
| gptkbp:binds |
gptkb:heparan_sulfate_proteoglycans
BCMA receptor TACI receptor |
| gptkbp:discoveredIn |
1998
|
| gptkbp:encodedBy |
TNFSF13 gene
|
| gptkbp:expressedIn |
lymphoid tissues
myeloid cells |
| gptkbp:function |
regulation of B cell development
stimulation of antibody production promotion of B cell survival |
| https://www.w3.org/2000/01/rdf-schema#label |
APRIL protein
|
| gptkbp:involves |
multiple myeloma
autoimmune diseases B cell malignancies |
| gptkbp:locatedOnChromosome |
17p13.1
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_ligand_superfamily
|
| gptkbp:molecularWeight |
~28 kDa
|
| gptkbp:postTranslationalModification |
proteolytic cleavage
|
| gptkbp:relatedTo |
BAFF protein
|
| gptkbp:secretes |
soluble cytokine
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:structure |
type II transmembrane protein
|
| gptkbp:UniProtID |
O75888
|
| gptkbp:bfsParent |
gptkb:TNFSF13
|
| gptkbp:bfsLayer |
7
|