APG-115 (MDM2-p53 inhibitor)
                        
                            GPTKB entity
                        
                    
                Statements (13)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:investigational_drug
                                        
                                         gptkb:small_molecule  | 
                            
| gptkbp:clinicalTrialPhase | 
                                    
                                        
                                            gptkb:Phase_I
                                        
                                         | 
                            
| gptkbp:developedBy | 
                                    
                                        
                                            gptkb:Ascentage_Pharma
                                        
                                         | 
                            
| gptkbp:indication | 
                                    
                                        
                                            gptkb:cancer
                                        
                                         | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            
                                            inhibits MDM2-p53 interaction
                                        
                                        
                                         | 
                            
| gptkbp:restored | 
                                    
                                        
                                            
                                            p53 tumor suppressor activity
                                        
                                        
                                         | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            oral
                                        
                                        
                                         | 
                            
| gptkbp:synonym | 
                                    
                                        
                                            
                                            APG-115
                                        
                                        
                                         | 
                            
| gptkbp:target | 
                                    
                                        
                                            gptkb:MDM2
                                        
                                         | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:Ascentage_Pharma
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            7
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            APG-115 (MDM2-p53 inhibitor)
                                        
                                        
                                         |