Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:ANP
Atrial natriuretic peptide |
| gptkbp:associatedWith |
heart failure
hypertension |
| gptkbp:category |
hormone
peptide natriuretic peptide |
| gptkbp:degradedBy |
gptkb:neprilysin
|
| gptkbp:discoveredIn |
1981
|
| gptkbp:effect |
increases glomerular filtration rate
increases renal sodium excretion inhibits antidiuretic hormone secretion inhibits renin release reduces aldosterone secretion |
| gptkbp:encodedBy |
NPPA gene
|
| gptkbp:foundIn |
gptkb:human
mammals |
| gptkbp:fullName |
Atrial Natriuretic Factor
|
| gptkbp:function |
regulation of blood pressure
vasodilation regulation of blood volume natriuresis |
| https://www.w3.org/2000/01/rdf-schema#label |
ANF (NPPA)
|
| gptkbp:length |
28 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_1p36.22
|
| gptkbp:predecessor |
preproANP
|
| gptkbp:promotion |
atrial stretch
high blood volume |
| gptkbp:recipient |
Natriuretic peptide receptor A (NPR-A)
|
| gptkbp:secretes |
cardiac atria
|
| gptkbp:structure |
peptide
|
| gptkbp:UniProtID |
P01160
|
| gptkbp:bfsParent |
gptkb:NKX2-5
|
| gptkbp:bfsLayer |
7
|