6-phosphofructokinase

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:activatedBy gptkb:AMP
fructose-2,6-bisphosphate
gptkbp:associatedWith gptkb:Tarui_disease
gptkbp:CASNumber 9001-80-3
gptkbp:catalyzes phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate
gptkbp:cofactor Mg2+
gptkbp:EC_number 2.7.1.11
gptkbp:foundIn gptkb:Bacteria
animals
plants
gptkbp:gene PFKL (liver)
PFKM (muscle)
PFKP (platelet)
https://www.w3.org/2000/01/rdf-schema#label 6-phosphofructokinase
gptkbp:inhibitedBy gptkb:ATP
citrate
gptkbp:location gptkb:cytoplasm
gptkbp:otherName phosphofructokinase-1
gptkbp:pathway glycolysis
gptkbp:product gptkb:ADP
fructose-1,6-bisphosphate
gptkbp:rate-limiting_step glycolysis
gptkbp:regulates allosteric
gptkbp:structure tetramer
gptkbp:substrate gptkb:ATP
fructose-6-phosphate
gptkbp:systematicName ATP:D-fructose-6-phosphate 1-phosphotransferase
gptkbp:UniProtID P08237 (human muscle isoform)
gptkbp:bfsParent gptkb:Phosphofructokinase
gptkbp:bfsLayer 7