Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antiviral drug
pyrimidine analogue |
| gptkbp:ATCCode |
J02AX02
|
| gptkbp:CASNumber |
gptkb:2022-85-7
|
| gptkbp:chemicalFormula |
C4H4FN3O
|
| gptkbp:contraindication |
pregnancy
renal impairment |
| gptkbp:developedBy |
gptkb:Roche
|
| gptkbp:discoveredBy |
1957
|
| gptkbp:eliminationHalfLife |
3-6 hours
|
| gptkbp:excretion |
gptkb:kidney
|
| https://www.w3.org/2000/01/rdf-schema#label |
5-fluorocytosine
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits fungal DNA and RNA synthesis
|
| gptkbp:metabolism |
cytosine deaminase
|
| gptkbp:molecularWeight |
129.10 g/mol
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
hepatotoxicity
gastrointestinal upset bone marrow suppression |
| gptkbp:synonym |
gptkb:flucytosine
|
| gptkbp:used_in |
gptkb:amphotericin_B
|
| gptkbp:usedFor |
treatment of cryptococcal meningitis
treatment of fungal infections |
| gptkbp:bfsParent |
gptkb:flucytosine
|
| gptkbp:bfsLayer |
6
|