4F2 heavy chain (SLC3A2)

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName 4F2 cell-surface antigen heavy chain
CD98
solute carrier family 3 member 2
gptkbp:associatedWith autoimmune diseases
cancer progression
gptkbp:disulfideBondWith light chain partners
gptkbp:encodedBy SLC3A2 gene
gptkbp:Entrez_Gene_ID 6520
gptkbp:expressedIn many tissues
gptkbp:formsComplexWith light chain amino acid transporters (LATs)
gptkbp:function amino acid transport
gptkbp:glycosylation yes
https://www.w3.org/2000/01/rdf-schema#label 4F2 heavy chain (SLC3A2)
gptkbp:locatedIn gptkb:plasma_membrane
gptkbp:locatedOnChromosome chromosome 11q12.3
gptkbp:molecularWeight 85 kDa
gptkbp:OMIM 600336
gptkbp:overexpressedIn various cancers
gptkbp:PDB 6IRS
gptkbp:role immune response
cell adhesion
integrin signaling
gptkbp:species gptkb:Homo_sapiens
gptkbp:transmembraneDomains yes
gptkbp:UniProtID P08195
gptkbp:bfsParent gptkb:large_neutral_amino_acid_transporter
gptkbp:bfsLayer 7