Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
3β-hydroxy-Δ5-steroid dehydrogenase
Δ5-4 isomerase |
| gptkbp:cofactor |
gptkb:NADH
NAD+ |
| gptkbp:EC_number |
1.1.1.145
|
| gptkbp:family |
gptkb:short-chain_dehydrogenase/reductase_family
|
| gptkbp:foundIn |
gptkb:adrenal_gland
gptkb:placenta gonads |
| gptkbp:fullName |
gptkb:3β-hydroxysteroid_dehydrogenase
|
| gptkbp:function |
catalyzes the oxidation and isomerization of 3β-hydroxysteroids
|
| gptkbp:gene |
gptkb:HSD3B1
gptkb:HSD3B2 |
| https://www.w3.org/2000/01/rdf-schema#label |
3β-HSD
|
| gptkbp:involvedIn |
steroid biosynthesis
|
| gptkbp:product |
gptkb:progesterone
gptkb:androstenedione |
| gptkbp:significance |
deficiency causes congenital adrenal hyperplasia
|
| gptkbp:substrate |
gptkb:pregnenolone
dehydroepiandrosterone |
| gptkbp:bfsParent |
gptkb:steroid_hormone_biosynthesis
|
| gptkbp:bfsLayer |
7
|