Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:17-beta-hydroxysteroid_dehydrogenase_type_2
gptkb:HSD17B2 |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:endometrial_cancer prostate cancer |
| gptkbp:biologicalProcess |
oxidoreductase activity
steroid metabolism |
| gptkbp:catalyzes |
oxidation of estradiol to estrone
oxidation of testosterone to androstenedione |
| gptkbp:cofactor |
gptkb:NADH
NAD+ |
| gptkbp:EC_number |
1.1.1.51
|
| gptkbp:encodedBy |
gptkb:HSD17B2_gene
|
| gptkbp:expressedIn |
gptkb:kidney
gptkb:placenta gptkb:prostate liver intestine |
| https://www.w3.org/2000/01/rdf-schema#label |
17-beta-HSD type 2
|
| gptkbp:locatedOnChromosome |
16q24.1
|
| gptkbp:location |
gptkb:endoplasmic_reticulum
|
| gptkbp:regulates |
local estrogen and androgen levels
|
| gptkbp:bfsParent |
gptkb:hsa:3265
|
| gptkbp:bfsLayer |
6
|