whole-genome bisulfite sequencing
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
sequencing technique
epigenomics method |
| gptkbp:alternativeTo |
reduced representation bisulfite sequencing
|
| gptkbp:analyzes |
cytosine methylation
|
| gptkbp:appliesTo |
genome-wide studies
|
| gptkbp:cannotDistinguish |
5-methylcytosine and 5-hydroxymethylcytosine
|
| gptkbp:detects |
5-methylcytosine
|
| gptkbp:developedBy |
2000s
|
| https://www.w3.org/2000/01/rdf-schema#label |
whole-genome bisulfite sequencing
|
| gptkbp:limitation |
high cost
DNA degradation complex data analysis |
| gptkbp:provides |
single-base resolution methylation data
|
| gptkbp:requires |
bioinformatics analysis
large amounts of DNA |
| gptkbp:sequencingPlatform |
gptkb:Illumina
gptkb:Oxford_Nanopore gptkb:PacBio |
| gptkbp:usedFor |
DNA methylation analysis
|
| gptkbp:usedIn |
cancer research
developmental biology plant epigenetics |
| gptkbp:uses |
high-throughput sequencing
bisulfite treatment |
| gptkbp:bfsParent |
gptkb:ENCODE_Data_Coordination_Center
|
| gptkbp:bfsLayer |
7
|