|
gptkbp:instanceOf
|
antiviral drug
|
|
gptkbp:approvedBy
|
1995
|
|
gptkbp:ATCCode
|
J05AB11
|
|
gptkbp:bioavailability
|
54%
|
|
gptkbp:brand
|
gptkb:Valtrex
|
|
gptkbp:CASNumber
|
124832-27-5
|
|
gptkbp:chemicalFormula
|
C13H20N6O4
|
|
gptkbp:contraindication
|
hypersensitivity to acyclovir
hypersensitivity to valaciclovir
|
|
gptkbp:developedBy
|
GlaxoSmithKline
|
|
gptkbp:eliminationHalfLife
|
2.5-3.3 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasGenericVersion
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
valaciclovir
|
|
gptkbp:isApprovedDrug
|
true
|
|
gptkbp:KEGGID
|
D02366
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits viral DNA polymerase
|
|
gptkbp:MedlinePlusID
|
a699040
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
324.33 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
B1 (Australia)
|
|
gptkbp:prodrugOf
|
gptkb:acyclovir
|
|
gptkbp:PubChem_CID
|
135398744
CHEMBL1448
DB00577
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
confusion
nausea
vomiting
abdominal pain
dizziness
headache
rash
|
|
gptkbp:UNII
|
7H092O90FY
|
|
gptkbp:usedFor
|
gptkb:herpes_simplex_virus
gptkb:varicella_zoster_virus
genital herpes
herpes zoster
herpes simplex
cold sores
herpes labialis
|
|
gptkbp:bfsParent
|
gptkb:Valaxa
gptkb:aciclovir
|
|
gptkbp:bfsLayer
|
7
|