|
gptkbp:instanceOf
|
antiviral drug
|
|
gptkbp:approvalYear
|
1995
|
|
gptkbp:approvedBy
|
gptkb:United_States
|
|
gptkbp:ATCCode
|
J05AB11
|
|
gptkbp:CASNumber
|
124832-27-5
|
|
gptkbp:chemicalFormula
|
C13H20N6O4
|
|
gptkbp:contraindication
|
hypersensitivity to acyclovir
hypersensitivity to valacyclovir
|
|
gptkbp:eliminationHalfLife
|
2.5-3.3 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:form
|
gptkb:tablet
oral suspension
|
|
gptkbp:genericName
|
gptkb:valacyclovir
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Valtrex
|
|
gptkbp:KEGGID
|
D02341
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:manufacturer
|
GlaxoSmithKline
|
|
gptkbp:mechanismOfAction
|
inhibits viral DNA polymerase
|
|
gptkbp:MedlinePlusID
|
a699032
|
|
gptkbp:metabolism
|
gptkb:acyclovir
|
|
gptkbp:pregnancyCategory
|
B
|
|
gptkbp:prescribes
|
treatment of cold sores
reduction of transmission of genital herpes
suppression of recurrent genital herpes
treatment of chickenpox in children
treatment of herpes labialis
treatment of herpes zoster
treatment of shingles
|
|
gptkbp:prescriptionRequired
|
yes
|
|
gptkbp:PubChem_CID
|
CHEMBL1433
135398744
DB00577
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
vomiting
abdominal pain
dizziness
headache
rash
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:UNII
|
61HXD2BB9L
|
|
gptkbp:usedFor
|
gptkb:herpes_simplex_virus
gptkb:varicella_zoster_virus
shingles
genital herpes
herpes zoster
cold sores
|
|
gptkbp:usedInImmunocompromisedPatients
|
yes
|
|
gptkbp:usedInPediatrics
|
yes
|
|
gptkbp:bfsParent
|
gptkb:valacyclovir
|
|
gptkbp:bfsLayer
|
6
|