Statements (21)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:drug
                                        
                                         | 
                            
| gptkbp:administeredBy | 
                                    
                                        
                                            
                                            oral
                                        
                                        
                                         | 
                            
| gptkbp:approvalYear | 
                                    
                                        
                                            
                                            2021
                                        
                                        
                                         | 
                            
| gptkbp:approvedBy | 
                                    
                                        
                                            gptkb:FDA
                                        
                                         | 
                            
| gptkbp:ATCCode | 
                                    
                                        
                                            
                                            L01EM05
                                        
                                        
                                         | 
                            
| gptkbp:genericName | 
                                    
                                        
                                            gptkb:umbralisib
                                        
                                         | 
                            
| gptkbp:manufacturer | 
                                    
                                        
                                            gptkb:TG_Therapeutics
                                        
                                         | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            
                                            PI3K delta and CK1 epsilon inhibitor
                                        
                                        
                                         | 
                            
| gptkbp:retired | 
                                    
                                        
                                            
                                            safety concerns
                                        
                                        
                                         | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            oral
                                        
                                        
                                         | 
                            
| gptkbp:sideEffect | 
                                    
                                        
                                            
                                            diarrhea
                                        
                                        
                                         infections elevated liver enzymes neutropenia  | 
                            
| gptkbp:usedFor | 
                                    
                                        
                                            
                                            treatment of follicular lymphoma
                                        
                                        
                                         treatment of marginal zone lymphoma  | 
                            
| gptkbp:withdrawn | 
                                    
                                        
                                            
                                            2022
                                        
                                        
                                         yes  | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:umbralisib
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            7
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            Ukoniq
                                        
                                        
                                         |