transposition of the great arteries

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:atrial_septal_defect gptkb:disease
gptkbp:affects	heart circulatory system
gptkbp:causedBy	abnormal development of the fetal heart
gptkbp:complication	gptkb:arrhythmia heart failure pulmonary hypertension
gptkbp:firstDescribed	1880s
gptkbp:hasDiagnosticMethod	gptkb:chest_X-ray echocardiogram cardiac catheterization
gptkbp:hasField	pediatric cardiology
gptkbp:hasMortalityWithoutTreatment	high in infancy
gptkbp:hasOrphanetID	997
gptkbp:hasRelatedCondition	gptkb:atrial_septal_defect gptkb:patent_ductus_arteriosus gptkb:ventricular_septal_defect
gptkbp:hasType	dextro-TGA (d-TGA) levo-TGA (l-TGA)
https://www.w3.org/2000/01/rdf-schema#label	transposition of the great arteries
gptkbp:ICD-10_code	Q20.3
gptkbp:inheritance	usually sporadic
gptkbp:MeSH_ID	D014143
gptkbp:OMIM	608808
gptkbp:prevalence	about 1 in 3,500-5,000 live births
gptkbp:prognosis	good with early surgical intervention
gptkbp:riskFactor	genetic factors maternal diabetes maternal rubella infection maternal age over 40
gptkbp:symptom	cyanosis shortness of breath failure to thrive poor feeding
gptkbp:synonym	gptkb:TGA
gptkbp:treatment	gptkb:balloon_atrial_septostomy surgical repair arterial switch operation prostaglandin E1 infusion
gptkbp:bfsParent	gptkb:Congenital_heart_disease
gptkbp:bfsLayer	7