thyroxine-binding globulin

GPTKB entity

Statements (26)
Predicate Object
gptkbp:instanceOf gptkb:protein
binding protein
gptkbp:abbreviation gptkb:TBG
gptkbp:affinity high for T4
lower for T3
gptkbp:binds gptkb:triiodothyronine_(T3)
thyroxine (T4)
gptkbp:deficiencyCauses thyroxine-binding globulin deficiency
gptkbp:discoveredIn 1952
gptkbp:encodedBy gptkb:SERPINA7_gene
gptkbp:excessCauses thyroxine-binding globulin excess
gptkbp:foundIn blood plasma
gptkbp:function transports thyroid hormones in blood
gptkbp:halfLife 5 days
https://www.w3.org/2000/01/rdf-schema#label thyroxine-binding globulin
gptkbp:locatedOnChromosome Xq22.3
gptkbp:molecularWeight 54 kDa
gptkbp:presentIn humans
other mammals
gptkbp:significance altered levels affect thyroid hormone availability
gptkbp:structure gptkb:protein
gptkbp:synthesisType liver
gptkbp:bfsParent gptkb:AT7
gptkb:T4
gptkb:triiodothyronine_(T3)
gptkbp:bfsLayer 6